Predicting Your Risk of Developing Oral Cancer
Heather discovered an oral lesion.
In this video, Heather reveals what happened next.
Introducing Straticyte. Straticyte is a test that accurately predicts a patient’s risk of developing oral cancer. Straticyte identifies precancerous lesions allowing you and your healthcare professional an opportunity to change the outcome.
And right now Straticyte is being offered on a complimentary basis for a limited time.
Ask your healthcare professional for more information about the Straticyte test.
Oral Cancer Statistics
- 70% of oral cancers are diagnosed at late stage
- 50% survival rate after five years
- Kills one person per hour in North America
- Survivors often have a poor quality of life including disfigurement and the inability to eat or drink normally
Risk factors
- Tobacco
- Abuse of alcohol
- Betel quid and areca nut
- HPV
- previous cancer
- Family history of squamous cell carcinoma (SCC)
- Sun exposure
Signs and Symptoms
- white patches, red patches or mixed red and white patches on the lips or in the mouth
- an ulcer or sore in the mouth or on the lip that doesn’t heal
- a lump or growth on the lip or in the mouth, including on the tongue
- thickening in the cheek
- bleeding in the mouth
- pain in the mouth that doesn’t go away
- persistent earache
- loose teeth
- dentures that no longer fit
- slurred speech
- swollen salivary glands
- swollen lymph nodes in the neck
- numbness or loss of sensation over the tongue or lips swelling of the jaw
Oral Lesion Types
Lichen Planus
- Common disorder
- Multiple presentations
- Less than 2% may become malignant over a 10 year period
- Necessary to distinguish from lichenoid dysplasia
Leukoplakia
- Leukoplakia is white plaque that cannot be scraped off, cannot be given another specific diagnosis and has no known cause (except tobacco use)
- 7 to 15% show dysplasia or a malignant tumor on biopsy
- Varying patterns, granular, wart like, thick, thin
Erythroleukoplakia
- This is an abnormal patch of red and white tissue that forms on mucous membranes in the mouth and may become cancer.
- Tobacco (smoking and chewing) and alcohol may increase the risk of erythroleukoplakia.
Erythroplakia
- Erythroplakia is defined as a red patch
- These may appear as smooth, velvety, granular or nodular lesions often with a well-defined margins
- The soft palate, the floor of mouth, the undersurface of tongue are the most common sites
- More common among middle aged to elderly persons and, especially among men
Actinic Cheilitis
- Effect of direct exposure to sunlight over a prolonged period of time
- Found primarily on the lower lip
- Common in outdoor workers, sun worshippers
- Deceptively benign in appearance, both clinically and histologically
Sublingual Keratosis
- Uncommon form of “leukoplakia”
- Thick white patch on the undersurface of the tongue or floor of mouth
- Initial biopsy is often benign
- High incidence of cancer
Proliferative Verrucous Leukoplakia (PVL)
- PVL is an uncommon form of progressive multifocal leukoplakia and has a high rate of malignant transformation to either squamous cell cancer or verrucous carcinoma
- PVL has a high probability of recurrence.
- More often seen in females
- Age range is 20-80
- Lining of the cheeks, floor of the mouth and tongue are often most affected
- 70% of patients will develop a cancer within a decade following diagnosis
Stomatitis in Reverse Smokers
- This is caused by extreme heat and tobacco in the mouth, most commonly from inserting the lit end in the mouth
- This is a common practice in parts of India, South America and the Philippines
- Older women are most often affected
- Differs from nicotinic stomatitis
- Accounts for 50% of malignancies in some parts of the world
“Oral Maxillofacial, ENT Surgeons and Oral Pathologists have confirmed a gap in diagnosis and are searching for something that will improve their patient’s outcomes. They see the devastation that happens with a late diagnosis of oral cancer. They want and need new technology that predicts a patient’s progression to oral cancer.”